Toxicology and pharmacological action of anabaena flos-aquae toxin.

نویسندگان

  • W W Carmichael
  • D F Biggs
  • P R Gorham
چکیده

Calves, rats, ducks, and goldfish given lethal oral doses of bacteria-free lyophilized cell suspensions of toxic Anabaena flos-aquae died as a result of respiratory arrest. Experiments with selected animals and pharmacological preparations showed that the main effect of the toxin was production of a sustained postsynaptic depolarizing neuromuscular blockade.

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عنوان ژورنال:
  • Science

دوره 187 4176  شماره 

صفحات  -

تاریخ انتشار 1975